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Shiue, S-J, Chien, I-Ling, Chan, N-L, Leu, W-M and Hu, N-T*. 2007.
Mutation of a key residue in the T2SS ATPase uncouples ATP hydrolysis
from protein translocation. Mol Microbiol 65: 401-412 |
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Shiue, S-J, Kao, K-M, Leu, W-M, Chen, L-Y, Chan, N-L and Hu, N-T*. 2006. XpsE oligomerization triggered by ATP binding, not hydrolysis, leads to its association with XpsL. EMBO J 25: 1426-1435. |
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Chen, Y, Shiue, S-J, Huang, C-W, Chang, J-L, Chien, Y-L, Hu, N-T* and Chan, N-L*. 2005. Structure and function of the XpsE N-terminal domain, an essential component of the Xanthomonas campestris type II secretion system. J Biol Chem 280: 42356-42363. |
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Lee, M-S, Chen, L-Y, Leu, W-M, R-J Shiau and Hu, N-T*. 2005. Associations of the major pseudopilin XpsG with XpsN (GspC) and secretin XpsD of Xanthomonas campestris pv. campestris type II secretion apparatus revealed by cross-linking analysis. J Biol Chem 280: 4585-4591. |
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Lee, H-M, Chen, J-R, Lee, H-L, Leu, W-M, Chen, L-Y and Hu, N-T*. 2004. Functional dissection of the XpsN (GspC) protein of the Xanthomonas campestris pv. campestris type II secretion machinery. J Bacteriol 186: 2946-2955. |
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Chen, Y, Hu, N-T* and Chan, N-L*. 2003. Crystallization and preliminary X-ray crystallographic analysis of the N-terminal domain of XpsE protein from Xanthomonas campestris, an essential component in the type II protein secretion machinery. Acta Crystallogr D Biol Crystallogr 60: 129-131. |
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Tsai, R-T, Leu, W-M, Chen, L-Y and Hu, N-T*. 2002. A reversibly dissociable ternary complex formed by XpsL, -M, -N of the Xanthomonas campestris pv. campestris. type II secretion apparatus. Biochem J 367:865-871. |
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Hu, N-T, Leu, W-M, Lee, M-S, Chen, A, Chen, S-C, Song, Y-L and Chen, L-Y*. 2002. XpsG, the major pseudopilin in Xanthomonas campestris pv. campestris, forms a pilus-like structure between cytoplasmic and outer membranes. Biochem J 365:205-211. |
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Lee, H-M, Tyan, S-W, Leu, W-M, Chen, L-Y, Chen, D C and Hu, N-T*. 2001. Involvement of the XpsN protein in formation of the XpsL-XpsM complex in Xanthomonas campestris pv. campestris type II secretion apparatus. J Bacteriol 183:528-535. |
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Lee, H-M, Wang, K-C, Liu, Y-L, Yew, H-Y, Chen, L-Y, Leu, W-M, Chen, D C and Hu, N-T*. 2000. Association of the cytoplasmic membrane protein XpsN with the outer membrane protein XpsD in the type II protein secretion apparatus of Xanthomonas campestris pv. campestris. J Bacterial 182:1549-1557. |
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Hu, N-T*, Hung, M-N, Chen, D C and Tsai, R-T. 1998. Insertion mutagenesis of XpsD, an outer membrane protein involved in extracellular protein secretion in Xanthomonas campestris pv. campestris. Microbiology 144:1479-1486 |
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| 國外會議論文 (近五年) |
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Hsueh, S-J and Hu, N-T. 2006. XpsE ATPase alleviated from suppression by its N-terminal domain through interaction with the N-terminal domain of XpsL. The FASEB Journal: Experimental Biology 2006R. A1365 (874.3). |
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Hsueh, S-J, Kao, K-M and Hu, N-T. 2005. Analysis of interactive relationship between XpsE and XpsLN. IUMS 2005: Microbes in A Changing World. B-1335. |
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Hsueh, S-J, Chen, Y, Chan, N-L and Hu, N-T. 2005. Crystal structures of XpsEN. IUMS 2005: Microbes in A Changing World. B-1337. |
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Hu, N-T, Chien, I-L, Lee, H-M, Chang, J-L, Chen, L-Y and Leu, W-M. 2003. XpsE of Xanthomonas campestris type II secretion apparatus. Japan/Taiwan Symposium on Molecular Biology of Functional Regulation in Plant and Microbe, Proceedings, p. 111-121. |
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| 國內會議論文 (近五年) |
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Hu, N-T. 2006. What do we know, and NOT know, about Type II protein secretion? The 11th Conference on Bacteriology, 2006. S-1. |
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Wei, C-J and Hu, N-T. 2006. Analysis of conformation change at the N domain of XpsE protein by utilizing fluorescence probes. The 11th Conference on Bacteriology, 2006. P-20. |
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Tseng, Y-N, Chao, Y-S and Hu, N-T. 2006. Significance of the N-terminal domain of XpsE in its interaction with XpsL analyzed by site-directed mutation. The 11th Conference on Bacteriology, 2006. P-47. |
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Hsueh, S-J and Hu, N-T. 2004. Type II secretion apparatus of Xanthomonas campestris: Analysis of interactive relationship between XpsLN and XpsE. Twelfth Symposium on Recent Advances in Cellular and Molecular Biology. |
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Chang, J-L and Hu, N-T. 2004. Type II section apparatus of Xanthomonas campestris: The N-terminal domain of XpsE interferes with secretion by making the full-length XpsE limited. Twelfth Symposium on Recent Advances in Cellular and Molecular Biology. |
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Hu, N-T, Chien, I-L, Lee, H-M and Chen, Y. 2003. How does the putative molecular motor GspE protein operate in the type II secretion apparatus? 2nd NHRI Conference on Bacterial Gene Regulation and Pathogenesis |
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Lee, H-M, Chen, J-R, Lee, H-L and Hu, N-T. 2003. Functional dissection of the N-terminal region of XpsN protein of the Xanthomonas campestris pv. campestris type II secretion machinery. 2nd NHRI Conference on Bacterial Gene Regulation and Pathogenesis. |
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Hsieh, S.-C., Wu, M-T and Hu, N-T. 2003. Cysteine-scanning mutagenesis of the transmembrane region of the XpsM protein which is involved in the type II secretion pathway of Xanthomonas campestris pv. campestris. Eleventh Symposium on Recent Advances in Cellular and Molecular Biology, P-173 |
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Tsai, R-T, Leu, W-M, Chen, L-Y and Hu, N-T. 2002. A reversibly dissociable ternary complex formed by XpsL, -M, -N of the Xanthomonas campestris pv. campestris. type II secretion apparatus. NHRI Conference on Bacterial Gene Regulation and Pathogenesis, p.27 |
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| 專利 |
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胡念台、侯豐男、洪秀妙、洪瑞宏，利用核多角病毒於家?細胞及?體中製造B型肝炎表面抗原之方法。中華民國專利第50644號，1991年9月。 |
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Chen, D C, Hu, N-T, Chen, Y-J and Hseu, T-H. Chimeric proteins with a cellulose binding domain. US Patent 6,407,208 B1, June 2002 |
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